Calmodulin and calcium signaling in potato tuberization: The role of membrane transporters in stress adaptation

Abstract

Potato tuberization is a complex developmental process influenced by environmental factors, such as light and temperature, as well as genetic and biochemical factors. Tuber formation is responsive to day length, with shorter days inducing tuberization more effectively than longer days. Potato tuber yield is regulated by signaling networks involving hormones, transcriptional regulators, and sugars. Calcium plays a pivotal role in this process. Elevated cytoplasmic calcium is detected by calcium sensors, including calmodulins (CaMs), calmodulin-like proteins (CMLs), Ca2+-dependent protein kinases (CDPKs), and calcineurin-B-like proteins (CBLs), promoting tuberization and growth. This review provides mechanistic insights into calcium signaling in potato tuberization, emphasizing its role in stress adaptation. This review further explores the role of calcium/calmodulin in stress response mechanisms and the membrane transporters that facilitate adaptation to environmental challenges like drought, cold, flooding, and heat stress, which are significant threats to potato production globally. Additionally, calcium signaling helps develop tolerance to both abiotic stresses and pathogens, ultimately enhancing plant immune responses to protect potato tubers.