OAK

운동 프로그램이 혈액투석 환자의 투석효율과 혈압에 미치는 효과

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Alternative Title
The Effect of Exercise Program on Dialysis Efficiency and Blood Pressure in Hemodialysis Patients -Systematic Review and Network Meta Analysis-
Abstract
This study attempted to identify the effects of exercise programs on dialysis efficiency and blood pressure in hemodialysis patients and to present empirical evidence through systematic literature review and network meta-analysis targeting domestic and foreign prior papers.
In the literature search, 1824 articles were retrieved from databases such as PubMed, EMBASE, Cochrane Library, Web of Science, and RISS. Among them, 26 documents that met the selection criteria of this study were selected, and meta-analysis and network meta-analysis were performed based on them. The result was as follows.
First, as a result of direct comparison meta-analysis, there was no significant effect on the dialysis efficiency of hemodialysis patients, but a significant effect on systolic and diastolic blood pressure.
Second, as a result of analysis by subgroup, aerobic exercise was effective for improving dialysis efficiency and combined exercise was effective for systolic and diastolic blood pressure in the analysis by exercise type. Also, in the analysis by exercise duration an exercise program of fewer than 3 months in dialysis efficiency and an exercise program of 3 to 6 months in systolic and diastolic blood pressure had a significant effect. In the analysis according to exercise time, there was no significant effect on dialysis efficiency and a 30-60 minute exercise program had a significant effect on systolic and diastolic blood pressure.
Third, as a result of network meta-analysis, aerobic exercise for dialysis efficiency and compound exercise for systolic/diastolic blood pressure had the highest probability of being the best exercise program and consistency was supported.
Fourth, as a result of the network meta-analysis for each subgroup, in the analysis by exercise duration, aerobic exercise of less than 3 months for dialysis efficiency and 3~6 months of combined exercise for systolic and diastolic blood pressure had the highest probability of being the best exercise program. Also, in the analysis by exercise time, 30 to 60 minutes of aerobic exercise for dialysis efficiency and 30 to 60 minutes of combined exercise for systolic and diastolic blood pressure had the highest probability of being the best exercise program.
In conclusion, in meta-analysis and network meta-analysis, aerobic exercise for less than 3 months and 30 to 60 minutes per session is effective for dialysis efficiency. For systolic and diastolic blood pressure, combined exercise for 3 to 6 months and 30 to 60 minutes per session was found to be the most effective.
Therefore, the exercise program for the management of dialysis efficiency and blood pressure in hemodialysis patients in the future is based on this evidence, so that combined exercise including aerobic exercise for 30 minutes or more should be performed 3 times a week, 30 to 60 minutes per session, and 3 to 6 months. It would be best to set.
Author(s)
유향숙
Issued Date
2021
Awarded Date
2021-08
Type
Dissertation
URI
https://repository.sungshin.ac.kr/handle/2025.oak/5174
http://dcollection.sungshin.ac.kr/common/orgView/000000014224
Alternative Author(s)
You. Hyang Sook
Affiliation
성신여자대학교 일반대학원
Department
일반대학원 체육학과
Advisor
최승욱
Table Of Contents
논문 개요

Ⅰ. 서 론 1
1. 연구 필요성 1
2. 연구 목적 5
3. 연구 가설 6
4. 용어 정의 6

Ⅱ. 이론적 배경 8
1. 체계적 문헌고찰(Systematic Review) 10
1) 체계적 문헌고찰의 개념 10
2) 체계적 문헌고찰 수행 단계 10
2. 네트워크 메타분석(Network Meta-Analysis) 11
1) 네트워크 메타분석의 개념 11
2) 네트워크 메타분석의 이해 12
3. 혈액투석과 혈액투석 환자 17
1) 혈액투석의 역사 18
2) 혈액투석의 개념과 원리 19
3) 혈액투석 환자의 투석효율 20
4) 혈액투석 환자의 혈압 22
5) 혈액투석 환자의 운동 24

Ⅲ. 연구방법 27
1. 연구 설계 27
2. 검색 전략과 문헌 검색 27
3. 문헌 선정과 선정기준 28
4. 자료 추출 및 코딩 29
5. 통계분석 29
1) 메타분석(Direct meta-analysis) 도구30
(1) 효과크기(Effect size) 계산 30
(2) 효과크기(Effect size) 해석 32
(3) 동질성 검증과 효과모형 33
(4) 보고 비뚤림 검증(Publication bias) 34
(5) 민감도 분석(Sensitivity analyses) 36
2) 네트워크 메타분석(Network meta-analysis) 도구 37
(1) 자료의 입력과 불러오기 38
(2) 네트워크 모델과 Network plot 38
(3) MCMC(Markov-Chain Monte Carlo) 시뮬레이션 39
(4) 일관성 검정(Inconsistency test) 40
(5) 숲 그림(Network forest plot) 41
(6) 프로그램 간 비교우위 선정(Program ranking) 41

Ⅳ. 연구결과 42
1. 체계적 문헌고찰 결과 42
1) 문헌검색 및 선정결과 42
2) 체계적 문헌고찰 결과 44
2. 메타분석(Direct meta-analysis) 결과 53
1) 선정문헌의 비뚤림 위험평가(Risk of bias) 53
2) 운동 프로그램의 전체 효과크기 58
3) 운동 프로그램의 하위집단별 효과크기 55
3. 네트워크 메타분석(Network Meta-Analysis) 결과 75
1) 운동 프로그램의 전체 네트워크 효과크기 75
2) 운동 프로그램의 하위집단별 네트워크 효과크기100

Ⅴ. 논의 149

Ⅵ. 결론 및 제언 155

참고문헌

ABSTRACT
Degree
Doctor
Publisher
성신여자대학교 일반대학원
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