The effect of perinatal ground and water exercises on the pregnant female mouse obesity gene

Abstract

The obesity gene (PPARs, Adiponectin) expression levels in prenatal rats were observed by differentiating the exercise type, and investigated how it affects on the mother mice. The goal of this study is to provide a preliminary data for the effective exercise routine and exercise prescription for pregnant women. The animals used in this study were 7-week-old male (n = 10) and female(n = 40) ICR type mice, which were supplied by an animal handling company (DY Biotech). After breeding, the pregnant mosue were randomly selected and divided into the Control Group(n=9), Ground Exercise Group (n=10), and Water Exercise Goup(n=10). The Ground Exercise and Water Exercise were conducted for 9-weeks at the frequency of 3days/week. .All data were analyzed utilizing the Statistical Package for the Social Sciences(SPSS, v.20.0). One-way analysis of variance(ANOVA) was used for inter-group comparisons. Statistical significance was considered when p value was less than 0.05(p <.05).

1. There is no statistical difference of the expression of PPAR- β in PPARs of muscles in the Control group and Ground Exercise group, but both groups have an increasing tendency. The statistical significance is(p<.05) between a Control group and WAter Exercise group that there are differences in the expression tendency depending on types of exercises. 2. There is no statistical difference of the expression of adiponectin of muscles in the Control Group and Ground Exercise Group, but both groups have an increasing tendency. The statistical significance is (p <.05) between the Control Group and Water Exercise Group that there are differences in the expression tendency depending on types of exercise.

The results conclude that the Ground exercise and water exercise positively affect pregnant mouse prior and after pregnancy. The water exercise increases the obesity genes, PPARs, and the expression of adiponectin that it prevents an excessive weight increase or obesity, thus, it affects positively on the health of a pregnant and embryo.