35% glycolic acid 필링관리가 노화피부의 탄력 및 피부상태에 미치는 효과와 자극평가

Abstract

Abstract

The Effect and Stimulate Appreciation to the skin and the realliance of the aging skin by the Skin Peeling Method of 35% glycolic acid.

Jung Soon Lee Major in Skin care and Obesity Management Dept. of Cultural industry Graduate School of Cultural industry Sungshin Women's University

The study performs comparative analysis to examine the differences in aging skin, including skin oil, moisture, roughness, elasticity and wrinkles after treating with peeling care on the test group 2 that used 35% Glycolic acid only, and with the test group 1, that applied physical stimulus using suction and 35% Glycolic acid. The test aims devising a new indicator for the aging skin care by identifying the skin response conditions resulting from stimulus and the care of 35% Glycolic acid through the comparison between skin irritation and subjective valuation concerning use effects felt by test groups.

Twenty people ranging in 40s-70s age group living in Seoul and Gyeonggi province are chosen as experimental object of which have no peeling care experience six months prior to the test or no sensitive skin confirmation through facial diagnosed conducted by experts and, the test was rendered a total eight times, between January 12 to February 19, 2010 and skin care was given in two-week intervals. Triple sense (Moritex Co: K10229) and Beauty Scope (D012) were used to check skin oil and moisture. The wrinkled areas of eyes and lips were magnified using a Beauty Scope camera lens for comparative study, and the deepest wrinkled area was measured.Check diagnose was performed at the times of 0th,4thand8th,whilemeasurementwasperformedthreetimesrepeatedly．Seven questions are prepared for questionnaire details for subjective evaluation and skin irritation to examine stimulus after peeling care and subjective evaluation of wrinkle effect using the Likert Scale, and the results are as follows．

First, the amount of skin oil has increased around the forehead area by 40.7% and 0.06% which showed a higher increase in the group 1 than the group 2. In the experiment conducted for moisture, the group 1 showed a significant increase compared with the group 2, showing 124.0% and 57.6% increase, respectively.(p<0.05). After conducting a pigmentation experiment, the group 2 demonstrated a more significant increase than the group 1 by 20.0% and 40.6% (p<0.001), respectively.In this study, the test group 2 showed a higher increase, since it appears that the group 1 demonstrates faster skin tone stability, which received more stimuli in terms of skin rejuvenation ability.

Second, elasticity has gradually increased by 108.5%，87.1% (p<0.001), respectively by the group 1 and 2, and demonstrated significant increase after carrying out eight times of experiments. In the case of wrinkles around the eyes, the group 1 and 2 have decreased by 33.4% and 36.4%,(p<0.01）respectively. After carryout out the experiments, wrinkles around the lips showed dramatic decrease of 51.7% and 35.8% in the group 1 and group 2 (p<0.05), respectively. In the wrinkles care, much more change could be found after stimulus. For the case of wrinkles around the lips, the effect in the wrinkles of the test group 1 was shown much more in the skin change even against much more stimulus, which was caused by the fact that the wrinkles around the eyes could not be added a stimulus deeply due to their sensitive characteristics, while the wrinkles around the lips could be added the strongest stimulus on the face. Therefore, the greatest difference appeared around the areas of lips.However, the change in P value appeared great in terms of skin change for the case of test group 2 as well. This was because 35% Glycolic acid was indicated as a stimulus sensitively when contacting the skin in the case of stimulus due to peeling. In most cases 10-15% Glycolic acid is commonly used, and the skin feels as a great stimulus against 35% Glycolic acid. This study aims to obtain the accurate research method on the response of skin aging that appears due to stimulus and the change according to regeneration recovery through experiments. Even in the changes after four times of care and eight times of care, there were great differences against the first stimulus, whereas no change after it. From this result, it can be expected that the raising the level in stages and aging skin care in 50% and 70% will give a great effect.Even though that P value differed in the moisture only, and differed great differences in the oil components on the forehead, elasticity, pigment and wrinkles around the lips, no difference was shown between two test groups. This was because that the skin responses the effect in the change even against peeling. Therefore, the group 1 showed the change due to peeling stimulus, and as a next step, the stimulus by the suction machine was added for much more effect and satisfaction.

Third, in terms of stimulus peeling, the group 1 and 2 responded that they experienced stimulus by 100.0％ and90.0％, respectively. The subjective stimulus response to irritation symptom were 2.80 and 2.47 in the test group 1 and the test group 2, respectively, which was higher in the test group 1. However, when asked questions whether they wish to receive the treatment again, 100% of respondents in both test groups responded that they would receive again, which means that they were willing to endure some level of inconveniences for a greater result in terms of skin care effect. Subjective valuation on skin change in the group 1 was 4.72 point, showing the highest point in the case of ‘the change associated with wrinkles’(M=4.90), in the order of ‘the degree of skin moisture’(M=4.80), ‘the degree of old keratin removal’(M=4.80),‘the degree of skin brightness’(M=4.70), ‘the change of the skin resilience’(M=4.70), and ‘a change in pore’(M=4.40). As a whole, they appeared to be very high in the part of subjective evaluation (p<0.05, p<0.01, p<0.001). The group 2 demonstrated the highest point at 3.88 point in ‘the degree of skin brightness’(M=4.30), in the order of ‘the degree of skin moisture(M=4.10), ‘the degree of old keratin removal’(M=3.80), ‘a change in wrinkles’(M=3.80), ‘the skin resilience’(M=3.80), and ‘a change in pores’(M=3.50)． Subjective valuation related to wrinkles showed the highest result around the lips and eyes (M=4.90)by 4.54 points on average by the group 1, followed by ‘the flabby wrinkles around the jaw’ (M=4.60), ‘a change in the facial form’(M=4.40), and ‘forehead wrinkles’(M=3.90). As a whole, they also appeared to be very high in the part of subjective evaluation (p<0.05, p<0.01, p<0.001). Subjective valuation regarding overall wrinkles of the group 2 was 3.76 points on average, and in the order of ‘around the lips(M=’4.40), ‘around the eyes’ (M=4.00) at most, followed by ‘a change in the facial form’(M=3.90), ‘the flabby wrinkles around the jaw’(M=3.30), and ‘forehead wrinkles’(M=3.20), showing statically significant difference between the two groups regarding the change in wrinkles. The group 1 showed a great change in general wrinkle changes (p<0.05, p<0.01, p<0.001)． As a conclusion, the positive response in the subjective evaluation requires further deeper researches on the peeling against aging skin using 50% and 70% Glycolic acid. And the stepwise care using 35%, 50% and 70% Glycolic acid is hopefully suggested. In this experiment, the change after four times of care showed greater difference than that after eight times of care, which indicates that the response was sensitive to the first stimulus, but after a certain time elapses, the response got insensitive by accommodation. Accordingly, the stepwise researches are suggested again, and it is desired that this research can be a turning point as a new care method for aging shin. In addition, it was felt that the clinical data on peeling as well as papers and data on post peeling care are not enough yet. This study has been restricted by a short experimental time and in sufficient precise skin measurement devices, which did not result in the sufficient observation of the experiment results. In the future, I wish opportunities to observe with an electron microscope or an optical microscope would be given to skin care specialists, and the precise measurement devices could be used as experimental devices to observe the change in the regeneration on the thick skin.